Title of article
Design, combinatorial chemical synthesis and in vitro characterization of novel urea based gelatinase inhibitors
Author/Authors
Yingsheng Zhang، نويسنده , , Dongmei Li، نويسنده , , Jon C. Houtman، نويسنده , , Donald T. Witiak، نويسنده , , Jo Seltzer، نويسنده , , Paul J. Bertics، نويسنده , , Charles T. Lauhon، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
2823
To page
2826
Abstract
A novel series of hydroxamate/urea-based inhibitors of gelatinases has been discovered via solid-phase combinatorial chemistry. SAR of P1′, P2′, and P3′ has been exploited and structures different from traditional succinate-based MMP inhibitors have been found.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790433
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