Title of article
Design, synthesis and DNA-cleavage of Gly-Gly-His-naphthalene diimide conjugates
Author/Authors
Vera Steullet، نويسنده , , Dabney W. Dixon، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
2935
To page
2940
Abstract
Naphthalene diimides with one and two metal-chelating Gly-Gly-His (GGH) motifs have been synthesized. Both conjugates induce single-stranded cleavage of plasmid pBR322 DNA in the presence of nickel and Oxone and are approximately 100-fold more efficient than Ni(II)•GGH-CONH2 itself.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790456
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