• Title of article

    Design, synthesis and DNA-cleavage of Gly-Gly-His-naphthalene diimide conjugates

  • Author/Authors

    Vera Steullet، نويسنده , , Dabney W. Dixon، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    6
  • From page
    2935
  • To page
    2940
  • Abstract
    Naphthalene diimides with one and two metal-chelating Gly-Gly-His (GGH) motifs have been synthesized. Both conjugates induce single-stranded cleavage of plasmid pBR322 DNA in the presence of nickel and Oxone and are approximately 100-fold more efficient than Ni(II)•GGH-CONH2 itself.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790456