Author/Authors :
Chi B. Vu، نويسنده , , Evelyn G. Corpuz، نويسنده , , Selvaluxmi G. Pradeepan، نويسنده , , Shelia Violette، نويسنده , , Catherine Bartlett، نويسنده , , Tomi K. Sawyer، نويسنده ,
Abstract :
The synthesis of a series of 1,2,4-oxadiazole analogs is discussed along with their ZAP-70 SH2 inhibitory activity. The tyrosine moiety in the original series has been replaced with nonpeptidic functional groups without a substantial loss of binding affinity.
