Author/Authors :
Steven De Jonghe، نويسنده , , Ilse Van Overmeire، نويسنده , , Samantha Poulton، نويسنده , , Chris Hendrix، نويسنده , , Roger Busson، نويسنده , , Serge Van Calenbergh، نويسنده , , Denis De Keukeleire، نويسنده , , Sarah Spiegel، نويسنده , , Piet Herdewijn، نويسنده ,
Abstract :
Short-chain sphinganine analogues 8, 9, 18, and 19, as well as 3-fluoro-sphingosine analogues 25 and 26 were synthesized. Their potential as sphingosine kinase inhibitors was investigated, in combination with previously synthesized sphingosine and fluorinated sphinganine analogues.
