Title of article
Pyrrolo[3,2-c]pyridine derivatives as inhibitors of platelet aggregation
Author/Authors
C. ALTOMARE، نويسنده , , L. Summo، نويسنده , , S. Cellamare، نويسنده , , A. V. Varlamov، نويسنده , , L. G. Voskressensky، نويسنده , , T. N. Borisova، نويسنده , , A. Carotti، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
581
To page
584
Abstract
A series of pyrrolo[3,2-c]pyridines, isosteres of the antithrombotic drug ticlopidine, has been synthesized and evaluated in vitro for the ability to inhibit aggregation of human platelet-rich plasma induced by adenosin 5′-diphosphate (ADP). Structure–activity relationships showed their antiplatelet effects to be related to the lipophilicity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790691
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