Title of article
Macrocarpins A–D, new cytotoxic nor-triterpenes from Maytenus macrocarpa
Author/Authors
Haydee Ch?vez، نويسنده , , Gladis Rodr?guez، نويسنده , , Ana Estévez-Braun، نويسنده , , Angel G. Ravelo، نويسنده , , Rafael Estévez-Reyes، نويسنده , , Antonio G. Gonzalez، نويسنده , , Jose L. Fdez-Puente، نويسنده , , Dolores Garc?a-Gr?valos، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
759
To page
762
Abstract
Macrocarpins A (1), B (2), C ( 3) and D ( 4), four new nor-triterpenes, have been isolated from the roots of Maytenus macrocarpa. The structures were established by spectroscopic examinations. Natural compounds 1, 2, 4 and the acetyl derivative 1a are cytotoxic against four tumoral cell lines with IC50 values ranging between 0.4 and 5.2 μM.
Figure 1. C–H long range correlations.
Figure 2. Selected NOEs observed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790730
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