Title of article
Design, synthesis, and structure–activity relationship studies of ATP analogues as DNA gyrase inhibitors
Author/Authors
Thomas Lübbers، نويسنده , , Peter Angehrn، نويسنده , , Hans Gmünder، نويسنده , , Silvia Herzig، نويسنده , , Josef Kulhanek، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
6
From page
821
To page
826
Abstract
We report herein the design and synthesis of ATP-analogues, namely 4-amino-pyrazolo[3,4-d]pyrimidines and 4-amino-pyrazolo[1,5-a][1,3,5]triazines, with DNA gyrase inhibitory activity. Among these series, some compounds exhibited promising antibacterial activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790744
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