Author/Authors :
Javier Soto، نويسنده , , Michel Bessodes، نويسنده , , Bruno Pitard، نويسنده , , Philippe Mailhe، نويسنده , , Daniel Scherman، نويسنده , , Gerardo Byk، نويسنده ,
Abstract :
We have developed new DNA complexing amphiphile based on Hoechst 33258 interaction with DNA grooves. The synthesis and physicochemical characterisation of lipid/DNA complexes, as compared to that of classical lipopolyamine for gene delivery, are described and discussed.