Title of article :
Discovery and evaluation of potent, cysteine-based α4β1 integrin antagonists
Author/Authors :
Sarah C. Archibald، نويسنده , , John C. Head، نويسنده , , Janeen M. Linsley، نويسنده , , John R. Porter، نويسنده , , Martyn K. Robinson، نويسنده , , Anthony Shock، نويسنده , , Graham J. Warrellow، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Pages :
3
From page :
993
To page :
995
Abstract :
Acyclic, disulphide derivatives of cysteine have been identified as moderately potent antagonists of α4β1-mediated leukocyte cell adhesion to VCAM. This communication describes how they were discovered from a simple -cystine derivative and using the structure–activity data of C*DThioPC* related cyclic peptides.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2000
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
790781
Link To Document :
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