Title of article
Synthesis and cytotoxic activity of acetogenin analogues
Author/Authors
Stéphane Rodier، نويسنده , , Yvan Le Huérou، نويسنده , , Brigitte Renoux، نويسنده , , Julien Doyon، نويسنده , , Pierre Renard، نويسنده , , Alain Pierré، نويسنده , , Jean-Pierre Gesson، نويسنده , , René Grée*، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
1373
To page
1375
Abstract
A set of 16 new simplified analogues of acetogenins has been designed based on: (i) the replacement of the bis THF moiety of these natural products by an ethylene glycol bis ether unit; (ii) the introduction of different lipophilic side chains (alkyl, aryl, dialkylamino, O-cholesteryl); (iii) the presence of the same terminal isolactone. In vitro cytotoxic activity against L1210 leukemia is reported.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790874
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