Title of article
Synthesis and biological properties of new 1β-methylcarbapenems having tetrazolothioether moiety
Author/Authors
Kye Jung Shin، نويسنده , , Ki Dong Koo، نويسنده , , Kyung Ho Yoo، نويسنده , , Dong Chan Kim، نويسنده , , Dong Jin Kim، نويسنده , , Sang Woo Park، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
5
From page
1421
To page
1425
Abstract
The synthesis and biological activities of a series of new 1β-methylcarbapenems 1a–l having tetrazolothioether moiety at C-5 position of pyrrolidine were described. Among these compounds, 1c showed the most potent antibacterial activity and advanced pharmacokinetics compared with imipenem and meropenem.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790887
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