Author/Authors :
Laval Chan، نويسنده , , Tomislav Stefanac، نويسنده , , Nathalie Turcotte، نويسنده , , Zhuhan Hu، نويسنده , , Yanmin Chen، نويسنده , , Jean Bédard، نويسنده , , Suzanne May، نويسنده , , Haolun Jin، نويسنده ,
Abstract :
Following the identification of first pass metabolism issues with our recently described anti-HCMV compounds, the naphthyridines and isoquinolines, we have designed a class of novel metabolically stable and orally bioavailable anti-HCMV agents, the dihydroisoquinolines.