• Title of article

    Acid catalyzed michael additions to artemisitene

  • Author/Authors

    Jingyuan Ma، نويسنده , , Everett Weiss، نويسنده , , Dennis E. Kyle، نويسنده , , Herman Ziffer، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    3
  • From page
    1601
  • To page
    1603
  • Abstract
    A series of 14-substituted-artemisinin and 9-epiartemisinin derivatives was prepared by a titanium-tetrachloride catalyzed addition of trimethylsilyl enol ethers to artemisitene. Several compounds were four to seven times more active than artemisinin against Plasmodium falciparum.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790931