Author/Authors :
Amir P. Tamiz، نويسنده , , Miles P. Smith، نويسنده , , Istvan Enyedy، نويسنده , , Judith Flippen-Anderson، نويسنده , , Mei Zhang، نويسنده , , Kenneth M. Johnson، نويسنده , , Alan P. Kozikowski، نويسنده ,
Abstract :
The synthesis and biological activity of a series of 6-substituted 1-azabicyclo[3.2.1]octanes are described. 1-Azabicyclo[3.2.1]octanes represent a new class of compounds that exhibit monoamine transporter inhibitory activity highly dependent on the overall topology and the absolute stereochemistry of the molecule