Author/Authors :
Kiyohiko Sugano، نويسنده , , Shoshin Yoshida، نويسنده , , Mikio Takaku، نويسنده , , Masayuki Haramura، نويسنده , , Ryoichi Saitoh، نويسنده , , Yoshiaki Nabuchi، نويسنده , , Hidetoshi Ushio، نويسنده ,
Abstract :
The intestinal permeability of benzamidine analogue thrombin inhibitor is correlated with molecular volume, lipophilicity (calculated log P and IAM column capacity factor), hydrogen bond acidity/basicity and dipolarity.