• Title of article

    Phenyloxazoles and phenylthiazoles as benzamide bioisosteres: synthesis and dopamine receptor binding profiles

  • Author/Authors

    Jürgen Einsiedel، نويسنده , , Christoph Thomas، نويسنده , , Harald Hübner، نويسنده , , Peter Gmeiner، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    2041
  • To page
    2044
  • Abstract
    Conformationally restricted benzamide bioisosteres were investigated when the aminomethylpyrrolidine derivative 4o proved D3 as well as D4 binding properties which were comparable to those of the atypical neuroleptics sulpiride and clozapine, respectively.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    791034