Title of article
Structure-based design and synthesis of phosphinate isosteres of phosphotyrosine for incorporation in Grb2-SH2 domain inhibitors. Part 2
Author/Authors
Clive V. Walker، نويسنده , , Giorgio Caravatti، نويسنده , , Alastair A. Denholm، نويسنده , , John Egerton، نويسنده , , Alex Faessler، نويسنده , , Pascal Furet، نويسنده , , Carlos Garcia-Echeverria، نويسنده , , Brigitte Gay، نويسنده , , Ed Irving، نويسنده , , Ken Jones، نويسنده , , Amanda Lambert، نويسنده , , Neil J. Press، نويسنده , , John Woods، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
2343
To page
2346
Abstract
A series of novel phosphinates, derived from 4-phosphonomethylphenylalanine, are described as isosteres of phosphotyrosine. Benzyl (or alkyl) phosphinomethylphenylalanine derivatives were prepared by alkylation of an amino acid P-H phosphinate.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791104
Link To Document