Title of article :
2,4,5-Trisubstituted imidazoles: novel nontoxic modulators of P-glycoprotein mediated multidrug resistance. Part 2[]
Author/Authors :
Chengzhi Zhang، نويسنده , , Sepehr Sarshar، نويسنده , , Edmund J. Moran، نويسنده , , Sonja Krane، نويسنده , , Jennifer C. Rodarte، نويسنده , , Khalid D. Benbatoul، نويسنده , , Ross Dixon، نويسنده , , Adnan M. M. Mjalli، نويسنده ,
Abstract :
Solution-phase combinatorial chemistry was applied to the optimization and development of clinical candidate OC144-093 (22), a novel and nontoxic modulator of P-glycoprotein mediated multidrug resistance.
