Title of article :
Antioxidant activity and xanthine oxidase inhibition activity of reductic acid: ascorbic acid analogue
Author/Authors :
Tadahiko Mashino، نويسنده , , Yasushi Takigawa، نويسنده , , Naomi Saito، نويسنده , , Liquing Q. Wong، نويسنده , , Masataka Mochizuki، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Abstract :
Reductic acid (2,3-dihydroxy-2-cyclopentenone, 1) decreased the ESR signal of 5,5-dimethyl-1-pyrroline 1-oxide (DMPO)-OH produced by hydroxyl radical and DMPO. 1 also inhibited lipid peroxidation initiated by cytochrome P450 and tert-butyl hydroperoxide. 1 inhibited xanthine oxidase activity, while ascorbic acid and 2-hydroxytetronic acid, an ascorbic acid analogue without side chain, did not.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
