Title of article
Design, synthesis, and intracellular localization of a fluorescently labeled DNA binding polyamide related to the antibiotic distamycin
Author/Authors
Sanjay K. Sharma، نويسنده , , Andrew T. Morrissey، نويسنده , , Gerald G. Miller، نويسنده , , William H. Gmeiner، نويسنده , , J. William Lown، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
769
To page
772
Abstract
The design and synthesis of the lipophilic (9) and fluorescent (10) conjugates of a structural analogue of distamycin and their in vitro cellular localization studies are reported. Confocal laser scanning microscopy (CLSM) indicates that 10 rapidly enters human ovarian adenocarcinoma (SKOV-3) cells with principal uptake in mitochondria and uniform cytoplasmic distribution.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791271
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