Author/Authors :
Andrew Cooke، نويسنده , , Alison Anderson، نويسنده , , Kirsteen Buchanan، نويسنده , , Alan Byford، نويسنده , , David Gemmell، نويسنده , , Niall Hamilton، نويسنده , , Petula McPhail، نويسنده , , Susan Miller، نويسنده , , Hardy Sundaram، نويسنده , , Peter Vijn، نويسنده ,
Abstract :
Propofol (2,6-diisopropylphenol) is a widely used intravenous anaesthetic that is formulated as an emulsion since it lacks water solubility. We report a range of water-soluble analogues of propofol, containing a para-alkylamino substituent, which retain good intravenous anaesthetic activity in rodents.
