Title of article :
New triterpenes, myrrhanol A and myrrhanone A, from guggul-gum resins, and their potent anti-inflammatory effect on adjuvant-induced air-pouch granuloma of mice
Author/Authors :
Ikuko Kimura، نويسنده , , Masayuki Yoshikawa، نويسنده , , Shinjiro Kobayashi، نويسنده , , Yoshitaka Sugihara، نويسنده , , Miho Suzuki، نويسنده , , Hideo Oominami، نويسنده , , Toshiyuki Murakami، نويسنده , , Hisashi Matsuda، نويسنده , , Vijay V. Doiphode، نويسنده ,
Abstract :
Myrrhanol A, a new triterpene isolated from guggul (Balsamodendron or Commiphora mukul Hook.)-gum resin, displays a potent anti-inflammatory effect on exudative pouch fluid, angiogenesis, and granuloma weights in adjuvant-induced air-pouch granuloma of mice. Its effects were more marked than those of hydrocortisone and the 50% aqueous methanolic extract of the crude drug. Myrrhanol A is a plausible candidate for a potent anti-inflammatory agent.
