Title of article
Anodic Oxidation of Ifosfamide and Cyclophosphamide: A Biomimetic Metabolism Model of the Oxazaphosphorinane Anticancer Drugs
Author/Authors
Angelo Paci، نويسنده , , Thierry Martens، نويسنده , , Jacques Royer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
3
From page
1347
To page
1349
Abstract
The electrochemical oxidation of anticancer drugs ifosfamide and cyclophosphamide produced in high yield methoxylated analogues of the key hydroxy-metabolites of these oxazaphosphorine prodrugs. The cytotoxicity of these compounds was evaluated, and found to be as high as the hydroxy-metabolite.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791406
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