• Title of article

    Isoindolines: A new series of potent and selective endothelin-A receptor antagonists

  • Author/Authors

    Paivi J. Kukkola، نويسنده , , Natalie A. Bilci، نويسنده , , Theodore Ikler، نويسنده , , Paula Savage، نويسنده , , Suraj S. Shetty، نويسنده , , Dominick DelGrande، نويسنده , , Arco Y. Jeng، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    1737
  • To page
    1740
  • Abstract
    1,3-Disubstituted isoindolines have been discovered as a new class of potent functional ETA selective receptor antagonists through pharmacophore analysis of existing nonpeptide endothelin antagonists. The structure–activity relationships for both the trans and the cis series of isoindolines are discussed.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2001
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    791492

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=791492