Title of article :
Synthesis and antiproliferative activity of epoxy and bromo compounds derived from estrone
Author/Authors :
Dragana R. Mili ، نويسنده , , Tatjana Kop، نويسنده , , Zorica Jurani ، نويسنده , , Miroslav J. Ga i ، نويسنده , , Bogdan A. Olaja، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
Based on biological properties of epoxyquinols from natural sources, bromo and epoxyquinols derived from estrone were synthesized and screened against Fem-X, HeLa and K562 cell lines. Evidence was found that the bromine atom and the epoxy moiety significantly increase the antiproliferative activity within the series.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
