Author/Authors :
Ingrid Devillers، نويسنده , , Georges Dive، نويسنده , , Catherine De Tollenaere، نويسنده , , Bénédicte Falmagne، نويسنده , , Bertrand de Wergifosse، نويسنده , , Jean-François Rees، نويسنده , , Jacqueline Marchand-Brynaert، نويسنده ,
Abstract :
A series of imidazolopyrazinones 3, substituted at C-2, and C-2/C-6, has been prepared. The compounds behaved as quenchers of superoxide anion. The more active compounds are structurally related to coelenterazine, a natural substrate of marine bioluminescence. Theoretical parameters based on Hartree–Fock instabilities have been examined.
