Title of article
Vinyl sulfonium as novel proteolytic enzyme inhibitor
Author/Authors
Gang Zhao، نويسنده , , Zhaohui S. Zhou، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
5
From page
2331
To page
2335
Abstract
Vinyl sulfoniums were synthesized from vinyl sulfides by methylation, and inhibited the proteolytic enzyme papain. Inhibition studies suggest a mechanism by which the vinyl sulfonium inhibitor covalently and irreversibly modifies the enzyme.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791626
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