Title of article
Hydrolysis of plasmid DNA catalyzed by Co(III) complex of cyclen attached to polystyrene
Author/Authors
Chul-Seung Jeung، نويسنده , , Chang Hwa Kim، نويسنده , , Kyeongsik Min، نويسنده , , Se Won Suh، نويسنده , , Junghun Suh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
2401
To page
2404
Abstract
Reactivity of the Co(III) complex of cyclen (CoCyc) in the hydrolytic cleavage of supercoiled pUC18 DNA leading to the formation of the corresponding open circular form was enhanced by >200 times upon attachment of CoCyc to cross-linked polystyrenes. Thus, half-lives as short as 40 min were achieved by the resin-based CoCyc in cleavage of the supercoiled DNA at 4 °C.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791642
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