Title of article :
Furans with basic side chains: synthesis and biological evaluation of a novel series of antagonists with selectivity for the estrogen receptor alpha
Author/Authors :
Deborah S. Mortensen، نويسنده , , Alice L. Rodriguez، نويسنده , , Jun Sun، نويسنده , , Benita S. Katzenellenbogen، نويسنده , , John A. Katzenellenbogen، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
3-Alkyl-2,4,5-triarylfurans with basic side-chain substituents were prepared as ligands for the estrogen receptor. Those analogues having the basic side chain on the C(4) phenol were high-affinity, ERα-selective antagonists.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters