Title of article
Synthesis and structure–activity relationships of thiotetronic acid analogues of thiolactomycin
Author/Authors
Subas M. Sakya، نويسنده , , Melani Suarez-Contreras، نويسنده , , John P. Dirlam، نويسنده , , Thomas N. OʹConnell، نويسنده , , Shigeru F. Hayashi، نويسنده , , Sheryl L. Santoro، نويسنده , , Barbara J. Kamicker، نويسنده , , David M. George، نويسنده , , Carl B. Ziegler، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
2751
To page
2754
Abstract
3-Acetyl analogues of thiolactomycin, a thiotetronic acid natural product, were synthesized and profiled against livestock pathogens. Some analogues showed improved activity over thiolactomycin against Staphylococcus aureus and comparable activity against Pasteurella multocida. Several semisynthetically modified analogues of thiolactomycin showed no improvement in activity over thiolactomycin.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791722
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