Title of article :
Studies on 3-deoxy- -manno-octulosonic acid 8-phosphate synthase using chorismate mutase inhibitors
Author/Authors :
Matthew R. Birck، نويسنده , , Arifa Husain، نويسنده , , Galina Ya. Sheflyan، نويسنده , , Bruce Ganem، نويسنده , , Ronald W. Woodard، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
The proposed cyclic mechanism of 3-deoxy- -manno-octulosonic acid 8-phosphate synthase and the mechanism of chorismate mutase share certain structural and electronic similarities. In this report, we examine several inhibitors of chorismate mutase for their efficacy against KDO 8-P synthase.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters