• Title of article

    Selenazolidines as Novel Organoselenium Delivery Agents

  • Author/Authors

    Yang Xie، نويسنده , , Megan D. Short، نويسنده , , Pamela B. Cassidy، نويسنده , , Jeanette C. Roberts، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    5
  • From page
    2911
  • To page
    2915
  • Abstract
    Two new classes of selenazolidine-4(R)-carboxylic acids (2-oxo and 2-methyl-SCAs) were synthesized and characterized. Both were designed as latent forms of selenocysteine, intended to provide a chemically superior delivery form for selenium. The prodrugs may be clinically useful when selenium supplementation at supranutritional levels is indicated, such as in cancer chemoprevention.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2001
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    791759