Title of article
Design, Synthesis, and SAR of Amino Acid Derivatives as Factor Xa Inhibitors[]
Author/Authors
Ting Su، نويسنده , , Yanhong Wu، نويسنده , , Brandon Doughan، نويسنده , , Zhaozhong J. Jia، نويسنده , , John Woolfrey، نويسنده , , Brian Huang، نويسنده , , Paul Wong، نويسنده , , Gary Park، نويسنده , , Uma Sinha، نويسنده , , Robert M. Scarborough، نويسنده , , Bing-Yan Zhu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
2947
To page
2950
Abstract
A series of potent and selective factor Xa inhibitors was synthesized using various readily available amino acids as central templates. The most potent compound displays IC50 of 3 nM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791766
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