Title of article
Synthesis and Antiproliferative Activity of Some Thiazolylbenzimidazole-4,7-diones
Author/Authors
Laura Garuti، نويسنده , , Marinella Roberti، نويسنده , , Annalisa Pession، نويسنده , , Emanuela Leoncini، نويسنده , , Silvana Hrelia، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
3
From page
3147
To page
3149
Abstract
Some thiazolylbenzimidazole-4,7-diones were synthesized and tested in vitro on two tumor cell lines. Compounds 2d and 2e show a very good activity on K562 cells, whereas compounds 2a and 2b are active on SW620 cells. The importance of the methoxy group on the quinone moiety is confirmed and the function at 4-position of the thiazole ring plays a determining role for the activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791812
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