Title of article
Synthesis and hiv-1 integrase inhibitory activities of catechol and bis-Catechol derivatives
Author/Authors
Romain Dupont، نويسنده , , Laurence Jeanson، نويسنده , , Jean-François Mouscadet، نويسنده , , Philippe Cotelle، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
3175
To page
3178
Abstract
Fourteen catechol and bis-catechol derivatives have been synthesised and tested for their HIV-1 inhibitory activities. The six more active molecules have been tested for their antiviral activity and cytotoxicity. We have found that bis-catechols 1 and 2 are the most active HIV-1 integrase inhibitor whereas the best antiviral compound is 4.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791818
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