Author/Authors :
Duane A. Burnett، نويسنده , , Mary Ann Caplen، نويسنده , , Margaret E. Browne، نويسنده , , Hongrong Zhau، نويسنده , , Scott W. Altmann، نويسنده , , Harry R. Davis Jr.، نويسنده , , John W. Clader، نويسنده ,
Abstract :
Fluorescent analogues of the cholesterol absorption inhibitor (CAI), Sch 58235, have been designed and synthesized as single enantiomers. Biological testing reveals that they are potent CAIs and are suitable tools for the investigation of the azetidinone CAI mechanism of action (MOA).