Title of article :
Synthesis and antibacterial evaluation of novel 2-[N-Imidoylpyrrolidinyl] carbapenems
Author/Authors :
Kouji Hattori، نويسنده , , Akira Yamada، نويسنده , , Satoru Kuroda، نويسنده , , Toshiyuki Chiba، نويسنده , , Masayoshi Murata، نويسنده , , Kazuo Sakane، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
The synthesis, antibacterial activity and DHP-susceptibility of a series of novel carbapenems, directly linked with heterocyclic moiety are described. Especially, the compounds linked pyrrolidine-carbapenem exhibited to have a good antibacterial activity against Staphylococcus aureus (MRSA) as well as Pseudomonas aeruginosa to maintain a good stability towards DHP-I.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
