Title of article
Synthesis and antibacterial evaluation of novel 2-[N-Imidoylpyrrolidinyl] carbapenems
Author/Authors
Kouji Hattori، نويسنده , , Akira Yamada، نويسنده , , Satoru Kuroda، نويسنده , , Toshiyuki Chiba، نويسنده , , Masayoshi Murata، نويسنده , , Kazuo Sakane، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
383
To page
386
Abstract
The synthesis, antibacterial activity and DHP-susceptibility of a series of novel carbapenems, directly linked with heterocyclic moiety are described. Especially, the compounds linked pyrrolidine-carbapenem exhibited to have a good antibacterial activity against Staphylococcus aureus (MRSA) as well as Pseudomonas aeruginosa to maintain a good stability towards DHP-I.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791978
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