Title of article
Synthesis of an α-Aminophosphonate Nucleoside as an Inhibitor of S-Adenosyl- -Homocysteine Hydrolase
Author/Authors
Jennifer A. Steere، نويسنده , , Peter B. Sampson، نويسنده , , John F. Honek، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
457
To page
460
Abstract
A phosphonic acid analogue of S-adenosyl- -homocysteine was prepared by a novel method and the epimeric mixture separated. Preliminary studies indicate that each epimer causes time-dependent inactivation of S-adenosyl- -homocysteine hydrolase, however each presented distinct kinetic characteristics.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791995
Link To Document