Title of article
α1-Adrenoceptor Agonists: The Identification of Novel α1A Subtype Selective 2′-Heteroaryl-2-(phenoxymethyl)imidazolines
Author/Authors
Michael J. Bishop، نويسنده , , Kevin A. Barvian، نويسنده , , Judd Berman، نويسنده , , Eric C. Bigham، نويسنده , , Deanna T. Garrison، نويسنده , , Michael J. Gobel، نويسنده , , Stephen J. Hodson، نويسنده , , Paul E. Irving، نويسنده , , James A. Liacos، نويسنده , , Frank Navas III، نويسنده , , David L. Saussy Jr.، نويسنده , , Jason D. Speake، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
471
To page
475
Abstract
Novel 2′-heteroaryl-2-(phenoxymethyl)imidazolines have been identified as potent agonists of the cloned human α1-adrenoceptors in vitro. The nature of the 2′-heteroaryl group can have significant effects on the potency, efficacy, and subtype selectivity in this series. α1A Subtype selective agonists have been identified.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791998
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