Title of article
New Method of Synthesis of Vinca Alkaloid Derivatives
Author/Authors
Jacques Fahy، نويسنده , , Valérie Thillaye du Boullay، نويسنده , , Dennis C. H. Bigg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
505
To page
507
Abstract
Vinblastine and vinorelbine analogues have been synthesised by reacting new versatile electrophilic vindoline derivatives with various 3-substituted indoles. The resulting compounds have been evaluated for their antimitotic properties, but exhibited less potent activities in comparison with the standard binary Vinca alkaloids.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792005
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