Title of article :
Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors
Author/Authors :
Amit S. Kalgutkar، نويسنده , , Scott W. Rowlinson، نويسنده , , Brenda C. Crews، نويسنده , , Lawrence J. Marnett، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
This paper describes SAR studies involved in the transformation of the NSAID meclofenamic acid into potent and selective cyclooxygenase-2 (COX-2) inhibitors via neutralization of the carboxylate moiety in this nonselective COX inhibitor.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
