Benzylidene Rhodanines as Novel Inhibitors of UDP-N-Acetylmuramate/ -Alanine Ligase
Author/Authors :
Mui Mui Sim، نويسنده , , Siew Bee Ng، نويسنده , , Antony David Buss، نويسنده , , Sharon Carmelita Crasta، نويسنده , , Kah Lin Goh، نويسنده , , Sue Kim Lee، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Pages :
3
From page :
697
To page :
699
Abstract :
Benzylidene rhodanines are novel inhibitors of UDP N-acetylmuramate/ -alanine ligase. They showed selective whole-cell activity against the Gram-positive MRSA but not against the Gram-negative Escherichia coli. Their cytotoxic effect on mammalian CHO cells was also evaluated.