Title of article :
Synthesis and Activity of a New Methoxytetrahydropyran Derivative as Dual Cyclooxygenase-2/5-Lipoxygenase Inhibitor
Author/Authors :
Sabine Barbey، نويسنده , , Laurence Goossens، نويسنده , , Thierry Taverne، نويسنده , , Joséphine Cornet، نويسنده , , Valérie Choesmel، نويسنده , , Céline Rouaud، نويسنده , , Gilles Gimeno، نويسنده , , Sylvie Yannic-Arnoult، نويسنده , , Catherine Michaux، نويسنده , , Caroline Charlier، نويسنده , , Raymond Houssin، نويسنده , , Jean-Pierre Hénichart، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Pages :
4
From page :
779
To page :
782
Abstract :
Dual COX-2/5-LO inhibitors are described as potential new therapeutic agents for inflammatory diseases. A surprisingly potent effect of a 5-LO pharmacophoric group on the COX-2 inhibition is presented as well as pharmacological in vitro and in vivo results.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2002
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
792067
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=792067
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