Title of article
Design, synthesis and bioactivity evaluation of tribactam β lactamase inhibitors
Author/Authors
Anton Copar، نويسنده , , Tadeja Prevec، نويسنده , , Borut An i ، نويسنده , , Toma Mesar، نويسنده , , Lovro Seli ، نويسنده , , Mateja Vilar، نويسنده , , Tom Solmajer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
971
To page
975
Abstract
Known carbapenem compounds with inhibitory effect towards β-lactamase enzymes are formed from bicyclical beta lactam structural scaffolds. On the basis of results from theoretical computational methods and molecular modelling we have designed and developed a synthetic route towards novel, biologically active tricyclic derivatives of carbapenems.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792114
Link To Document