Title of article
Benzimidazole-4,7-diones as Inhibitors of Protozoal (Toxoplasma gondii) Purine Nucleoside Phosphorylase
Author/Authors
Frédéric Alvarez، نويسنده , , Arnaud Ghérardi، نويسنده , , Pascal Nebois، نويسنده , , Marie-Elizabeth Sarciron، نويسنده , , Anne-Françoise Pétavy، نويسنده , , Nadia Walchshofer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
977
To page
979
Abstract
Benzimidazole-4,7-diones derivatives substituted at 1- and/or 2-position have been synthetized and tested as inhibitors of purine nucleoside phosphorylase (PNP), isolated from two strains of Toxoplasma gondii (RH and ME 49). They were identified as inhibitors of both enzymes.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792115
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