Title of article
Reductive amination products containing naphthalene and indole moieties bind to melanocortin receptors
Author/Authors
Felikss Mutulis، نويسنده , , Ilze Mutule، نويسنده , , Maris Lapins، نويسنده , , Jarl E. S. Wikberg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
1035
To page
1038
Abstract
Presumed pharmacophoric groups of melanocortin peptides (naphthalene, amino or guanidine, and indole moieties) were combined in mimetics molecules looking for their favorable location for activity at melanocortin (MC) receptors. Twenty-two compounds were prepared and tested. The best of these displayed micromolar affinities for the MC receptors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792132
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