Title of article :
Thalidomide and its analogues as cyclooxygenase inhibitors
Author/Authors :
Tomomi Noguchi، نويسنده , , Rumiko Shimazawa، نويسنده , , Kazuo Nagasawa، نويسنده , , Yuichi Hashimoto، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
Thalidomide showed cyclooxygenase (COX)-1/2 inhibitory activity with a potency comparable to that of aspirin. Structural development studies of thalidomide resulted in potent COX-1/2 inhibitors, and COX-1-selective and COX-2-selective inhibitors.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
