Title of article
Thalidomide and its analogues as cyclooxygenase inhibitors
Author/Authors
Tomomi Noguchi، نويسنده , , Rumiko Shimazawa، نويسنده , , Kazuo Nagasawa، نويسنده , , Yuichi Hashimoto، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
1043
To page
1046
Abstract
Thalidomide showed cyclooxygenase (COX)-1/2 inhibitory activity with a potency comparable to that of aspirin. Structural development studies of thalidomide resulted in potent COX-1/2 inhibitors, and COX-1-selective and COX-2-selective inhibitors.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792135
Link To Document