Title of article
New thiazane and thiazolidine PNA monomers: synthesis, incorporation into PNAs and hybridization studies
Author/Authors
Sarah Bregant، نويسنده , , Fabienne Burlina، نويسنده , , Gérard Chassaing، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
1047
To page
1050
Abstract
New constrained PNA monomers containing a substituted thiazolidine or a thiazane ring were synthesized and incorporated in the center of a 9-mer homothymine PNA. The PNA/DNA hybrids stability was studied by UV-melting experiments which showed that the presence of the modified unit destabilizes the PNA/DNA triplexes.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792136
Link To Document