Author/Authors :
Takashi Ishiyama، نويسنده , , Shin Iimura، نويسنده , , Satoru Ohsuki، نويسنده , , Kouichi Uoto، نويسنده , , Hirofumi Terasawa، نويسنده , , Tsunehiko Soga، نويسنده ,
Abstract :
To synthesize new highly active taxoids, we designed and synthesized 9β-dihydro-9,10-acetal taxoids. In vitro study of these analogues clearly showed them to be more potent than docetaxel.