Title of article :
Shikonin derivatives: synthesis and inhibition of human telomerase
Author/Authors :
Qun Lu، نويسنده , , Weijun Liu and Xiaofeng Shang، نويسنده , , Jian Ding، نويسنده , , Junchao Cai، نويسنده , , Wenhu Duan، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
We synthesized -shikonin, shikonin, alkanin, and their cyclo-derivatives and acyl-derivatives. These compounds have low cytotoxicity, as well as inhibitory activity against the telomerase enzyme, except cyclo-derivatives
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
